Preval HealthComparison
Marek Health, and the alternatives
What Marek Health offers and costs as of October 2026, how it handles cholesterol and heart health, and who should pick which.
Online, nationwide in the US. Protocols written by a board-certified preventive cardiologist.
TL;DR
Marek Health runs a coach-guided optimization program that covers hormones, weight, performance and heart health, with a wide menu of medicines that includes rosuvastatin, ezetimibe, bempedoic acid and Repatha. It suits people who want one program for many goals. If lowering your LDL cholesterol (LDL-C) and ApoB is the goal that matters most, a practice that does only lipid care builds everything around that one number.
What Marek Health offers (as of October 2026)
- Guided Optimization. A clinically supervised program that Marek describes as including physician-prescribed TRT, GLP-1 medicines and therapeutic peptides. A Marek health coach builds a custom lab panel, checks in monthly and coordinates refills and follow-up labs.
- Heart Health program. After testing and a consultation with a licensed medical provider, clients may be eligible for rosuvastatin, ezetimibe, bempedoic acid, Repatha, fenofibrate, omega-3 ethyl esters, telmisartan, nebivolol, propranolol, canagliflozin and GLP-1 therapy, per Marek's heart-health page.
- Cost. Marek's heart-health page shows $299 to start treatment online and requires a minimum $450 lab panel purchase. Medicines cost extra. Marek doesn't bill insurance; its FAQ says many clients pay with an FSA or HSA.
- Requirements. Marek asks every client for a copy of an annual physical from an MD, DO, PA or NP before starting and continuing treatment. Guided Optimization runs in all 50 states, with some treatments limited by state.
- Self-service labs. You can also order lab panels yourself and review the results without a treatment plan.
Verified on marekhealth.com (home, heart health and FAQ pages). Last checked October 12, 2026. Prices and programs change, so confirm details with the company directly.
Why we start with cholesterol
Heart disease kills more Americans than any other cause, year after year, according to the CDC. Most of it starts with cholesterol-carrying particles (the ones tagged by ApoB, a protein on LDL and its cousins) lodging in artery walls.
Genetic, observational and randomized trial evidence all point the same way: these particles cause atherosclerosis, and the longer and higher your exposure, the more plaque builds (European Atherosclerosis Society consensus, Ference and colleagues, 2017). In the Cholesterol Treatment Trialists' analysis of statin trials, each 39 mg/dL drop in LDL-C cut major heart attacks and strokes by about a fifth. The FOURIER (2017) and ODYSSEY OUTCOMES (2018) trials showed that PCSK9 inhibitors lower events further on top of a statin.
Few longevity strategies have that much evidence behind them, so we put all of our attention there, with an LDL and ApoB goal, the right medicine to reach it, and rechecks that keep you there.
Side by side
| Question | Marek Health | Preval Health |
|---|---|---|
| Main focus | Broad optimization: hormones, weight, performance, sleep, heart health | Prescription lipid management only |
| Who guides you | A health coach, with a licensed provider for prescriptions | Licensed clinicians following protocols written by a board-certified preventive cardiologist |
| Cholesterol medicines | Rosuvastatin, ezetimibe, bempedoic acid, Repatha and others | Statins, ezetimibe, bempedoic acid, and PCSK9 inhibitors: Lerochol, Repatha, Praluent, Lipfendra |
| The goal | Set within a broader optimization plan | An LDL and ApoB goal set for you, rechecked after every change until you reach it |
| Genetics | Not listed on the pages we reviewed | Optional longevity genetic testing, ordered at your first visit |
| Insurance | Doesn't bill insurance; FSA or HSA often works | Cash practice; no insurance billing |
Marek Health may suit you if
- You want hormones, weight and performance handled in one program
- You like a health coach checking in every month
- You already have a doctor for an annual physical
Preval Health may suit you if
- Your LDL, ApoB, or Lp(a)-related risk is high and you want a specific goal
- You're not at goal on a statin, or can't tolerate one
- You may need a PCSK9 inhibitor (Lerochol, Repatha, Praluent, or Lipfendra)
- You want to know what your genes add, through optional longevity genetic testing
Marek offers a wide range of cholesterol medicines, and that serves plenty of people well. We focus every visit on one question: is your ApoB low enough yet, and if not, what changes next?
We focus only on lipid care. A board-certified preventive cardiologist wrote our treatment protocols, and licensed clinicians in our partner telehealth network deliver care and write prescriptions. We order ApoB and Lp(a) at the start, set your goal, and step treatment up from statins through PCSK9 inhibitors until you reach it. We run as a cash practice: $99 a month for care, medicines at cash prices, and no insurance billing.
Common questions
What is Marek Health?
Marek Health runs a telehealth optimization program called Guided Optimization. A health coach builds a lab panel and plan, and licensed providers prescribe treatments that include TRT, GLP-1 medicines, peptides and heart-health medicines. It also sells self-service lab panels and supplements.
How much does Marek Health cost?
As of October 2026, Marek's heart-health page shows $299 to start treatment online and requires a minimum $450 lab panel purchase. Medicines and follow-up labs add to that. Marek doesn't bill insurance, though its FAQ says many clients use an FSA or HSA.
Does Marek Health prescribe cholesterol medicine?
Yes. Marek's heart-health page lists rosuvastatin, ezetimibe, bempedoic acid, Repatha and fenofibrate among the options clients may qualify for after testing and a consultation with a licensed provider.
Does Marek Health require an annual physical?
Yes. Marek's FAQ asks for a copy of an annual physical from an MD, DO, PA or NP before you start and to continue treatment.
How is Preval Health different from Marek Health?
Marek covers many goals at once through coaching. Preval Health focuses only on prescription lipid management. We set an LDL and ApoB goal for you, recheck after every change, and step up from statins through PCSK9 inhibitors such as Lerochol, Repatha, Praluent and Lipfendra until you reach it. A board-certified preventive cardiologist wrote the protocols, and licensed clinicians deliver care. We run as a cash practice.
Treatment to a goal, with regular rechecks.
We are gradually rolling out services and accepting a limited number of patients. Join the waitlist to be among the first.
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